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Purpose: Pembrolizumab has previously shown antitumor activity against programmed death ligand 1 PD-L1 -positive metastatic castration-resistant prostate cancer mCRPC. Here, we assessed the antitumor activity and safety of pembrolizumab in three parallel cohorts of a larger mCRPC population. Cohort 3 enrolled patients with bone-predominant disease, regardless of PD-L1 expression. All patients received pembrolizumab mg every 3 weeks for up to 35 cycles. Secondary end points included disease control rate, duration of response, overall survival OS , and safety.
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Community Medical Associates Case Study

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Community Medical Associates Case Study | Eddusaver

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